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Vyepti vs other CGRPs?

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Hi all, I have NDPH & chronic migraine, long story short I’ve tried a ton of medications / treatments and the only thing that’s taken me from a daily 8/10 to 6/10 and helped at all has been Vyepti infusions. I’ve had 2 now, but my neurologist has stopped me having any more as I‘ve had a bad anaphylactic reaction both times. We’re going to discuss alternatives, presumably the monthly injections or daily tablets. Has anyone else had an allergic reaction to Vyepti? He said mine is very rare and he’s never seen it before. I’d also love to know if anyone’s had better results / pain improvement from the monthly injections or tablet forms rather than the infusion? We went for Vyepti as it’s meant to be the most effective, so I’m really worried I won’t get anywhere near the same results from the other forms :(

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Subreddit
r/migraine
Posted
Feb 12, 2026 at 1:36 PM UTC
LeadScore: 30question

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Condition
new daily persistent headache (NDPH), chronic migraine