Prometrium for perimenopause - regular vs. extended release
Post Content
Late 30sF. I FINALLY convinced my doctor to let me try Prometrium after several other medications (wellbutrin, deblitane, effexor, zoloft, etc). YMMV, but it has helped a lot with night sweats, mood, and hot flashes. 100mg/1x a day. I have noticed that I get VERY tired right after taking it. I could get a lower dosage compounded (50? 75?), or I could get an extended release formulation. Has anyone tried extended release?
Details
- Subreddit
- r/Menopause
- Author
- u/Middle_Violinist_5
- Posted
- Feb 12, 2026 at 7:11 PM UTC
LeadScore: 55question
AI Analysis
- Medication
- Prometrium, progesterone
- Condition
- perimenopause, hot flashes, night sweats, mood symptoms
- Geography
- us likely