Any success with anti-nausea besides Zofran?
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Nausea is my #1 migraine symptom. When I told my neurologist that Zofran doesn’t really work for me, he was surprised. I find that it can take the edge off of nausea if I have already treated the migraine with a rescue med. But if I am going to vomit from a migraine, there is no way that Zofran will stop it for me. Is this typical for others? Are there any other meds you have tried that work better than Zofran if it doesn’t work for you? I know that no anti-nausea drug will work 100% of the time, but people find relief from nausea and vomiting during pregnancy with these meds, so I have to believe something must work for migraine nausea, too.
Details
- Subreddit
- r/migraine
- Author
- u/mugnmuffin22
- Posted
- Feb 12, 2026 at 2:08 PM UTC
LeadScore: 50question
AI Analysis
- Medication
- ondansetron (Zofran)
- Condition
- migraine, nausea, vomiting
- Geography
- us likely