How to deal with a trans friend that has never been dating and is jealous of my relationship?

So my wife and I have this friend, let's call her S. S. is 36 years old and is non binary trans femme, outed a couple of years ago and we have been nothing but supportive. It hasn't been easy for S. with hormones and her location of work, new pronouns, a new name and so on. She lives kinda far away but we see her a couple of times a year and she plays games with my wife via discord during the week. Lately she has been distant, yesterday she confided in my wife that she compares her life to my wifes all the time and she wishes she had what my wife has: a long lasting relationship and marriage, a stable home and a job she enjoys. I am also very succesful in my job which she also told my wife she is jealous about. The hardest part on her is the fact that she never dated or had a relationship and seeing us so happy hurts her big time. Also, she is very insecure about her appearance, trying out more feminin styling/makeup/clothing but she fears she will never come close to passing since transitioning started so late for her. Since she is a very good friend of ours and you all are way more familiar with the struggles a trans person is going through, what can I do to help? Non native english speaker, sorry for errors.